On this page you will find links to key research in the area of identifying home hazards and effective interventions. You will also find links to research that was fully or partially sponsored by the Asthma Regional Council.
Control of asthma triggers in indoor air with air cleaners: a modeling analysis.
Myatt TA, Minegishi T, Allen JG, Macintosh DL. Environmental Health, 2008
Asthma Triggers and Effectiveness of Home Interventions
Chemicals and Body Burden
The Centers for Disease Control and Prevention (CDC) has conducted biomonitoring for chemical exposures in the U.S. population since 1999. CDC has published the Third National Report on Human Exposure to Environmental Chemicals.
The Environmental Working Group conduct testing in humans for pesticides, plastics, flame retardants and other consumer products. The also product consumer shopping guides for such things as pesticides in food.
Chemicals in Households
Silent Spring’s Household Air and Dust Study Silent Spring researchers have take indoor air and dust samples from 120 homes on Cape Cod and measured the concentrations of 89 chemicals widely used in pesticides, detergents, plastics, furniture, and cosmetics. The chemicals tested are identified as endocrine disrupting compounds, which mimic or interfere with human hormones, sometimes affecting cell growth and development. The number of chemicals detected in the homes averaged 19 for air and 26 for dust.
Asthma, Pests, and Pesticides
Ely, Elissa. House Dust Yields Clue to Asthma: Roaches. New York Times. 6 April 2009.
Kim J, Merry AC, Nemzek JA et al. Eotaxin Represents the Principal Eosinophil Chemoattractant in a Novel Murine Asthma Model Induced by House Dust Containing Cockroach Allergens. The Journal of Immunology. 2001; 167(5): 2808-2815.
Phipatanakul W, Eggleston PA, Wright EC et al. Mouse allergen. I. The prevalence of mouse allergen in inner-city homes. Journal of Allergy and Clinical Immunology. 2000; 106 (6): 1070-1074.
Rosenstreich DL, Eggleston P, Kattan M et al. The Role of Cockroach Allergy and Exposure to Cockroach Allergen in Causing Morbidity among Inner-City Children with Asthma. New England Journal of Medicine. 1997; 336 (19): 1356-1363.
Salam MT, Li YF, Langholz B, Gilliland FD. Early-life environmental risk factors for asthma: findings from the Children’s Health Study. Environmental Health Perspectective. 2004; 112(6): 760-765.
Salameh PR, Baldi I, Brochard P, et al. Respiratory symptoms in children and exposure to pesticides. European Respiratory Journal. 2003; 22: 507-512.
Stout DM, Bradham KD, Egeghy PP et al. American Healthy Homes Survey: A National Study of Residential Pesticides Measured from Floor Wipes. Environmental Science & Technology. 2009; 43 (12), pp 4294-4300.
Weiner BP, and RM Worth. Insecticides: Household use and respiratory impairment. Hawaii Medical Journal. 1969; 28(4): 283-285.
Interventions to Reduce Allergen Levels and Improve Health Outcomes
Crain EF, Walter M, O’Connor GT et al. Home and allergic characteristics of children with asthma in seven U.S. urban communities and design of an environmental intervention: the Inner-City Asthma Study. Environmental Health Perspectives. 2002; 110(9): 939-45.
Kass D, McKelvey W, Carlton E et al. Effectiveness of an Integrated Pest Management Intervention in Controlling Cockroaches, Mice and Allergens in New York City Public Housing. Environmental Health Perspectives. 15 April 2009.
Kattan M, Stearns SC, Crain EF et al. Cost-effectiveness of a home-based environmental intervention for inner-city children with asthma. Journal of Allergy and Clinical Immunology. 2005; 116 (5): 1058-1063.
Krieger J, Takaro TK, Song L et al. A Randomized Controlled Trial of Asthma Self-management Support Comparing Clinic-Based Nurses and In-Home Community Health Workers. Archives of Pediatrics and Adolescent Medicine. 2009; 163 (2): 141-149.
Krieger JW, Takaro TK, Allen C et al. The Seattle-King County healthy homes project: implementation of a comprehensive approach to improving indoor environmental quality for low-income children with asthma. Environmental Health Perspectives. 2002; 110 (suppl. 2): 311-322.
Krieger, JW Takaro TK, Song L, Weaver M. The Seattle-King County Healthy Homes Project: A Randomized, Controlled Trial of a Community Health Worker Intervention to Decrease Exposure to Indoor Asthma Triggers. American Journal of Public Health. 2005; 95 (4): 652-59.
Levy, Jonathan I., Brugge, Doug, Peters, Junenette L., et al. A community-based participatory research study of multifaceted in-home environmental interventions for pediatric asthmatics in public housing. Social Science & Medicine. 63 (2006): 2191-2203.
Miller DM and Meek F. Cost and Efficacy Comparison of Integrated Pest Management Strategies with Monthly Spray Insecticide Applications for German Cockroach (Dictyoptera: Blattellidae) Control in Public Housing, Journal of Economic Entomology. 2004; 97(2): 559-569.
Morgan WJ, Crain EF, Gruchalla RS et al. Results of a home-based environmental intervention among urban children with asthma. New England Journal of Medicine. 2004; 351(11): 1068-1080.
National Center for Healthy Housing. Comparison of Cost and Effectiveness for Cockroach Control. 2007.
National Center for Healthy Housing. Boston Public Housing: Partnerships and Policy Advances.
Phipatanakul W, Cronin B, Wood RA et al. Effect of environmental intervention on mouse allergen levels in homes of inner-city Boston children with asthma. Annals of Allergy and Asthma Immunology. 2004; 92(4): 420-425.
Pongracic JA, Visness CM, Gruchalla RS et al. Effect of mouse allergen and rodent environmental intervention on asthma in inner-city children. Annals of Allergy, Asthma, and Immunology. 2008; 101 (1): 35-41.
Sandel M, Batcheller A, Richman I et al. Can Integrated Pest Management Impact Urban Children with Asthma? Boston University School of Medicine. Department of Pediatrics. 2005.
Williams MK, Barr DB, Camann DE et al. An Intervention to Reduce Residential Insecticide Exposure during Pregnancy among an Inner-City Cohort. Environmental Health Perspectives. 2006; 114(11): 1684-1689.
Wu F, Takaro TK.Childhood Asthma and Environmental Interventions Environmental Health Perspectives Mini-Monograph, 2007; 115 (6): 971-975.